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(2019). Incidence and Risk Factors of Brief Resolved Unexplained Events in Infants presenting to Pediatrics Department of Bab Elsharya University Hospital. Al-Azhar Journal of Pediatrics, 22(4), 629-653. doi: 10.21608/azjp.2019.303590
. "Incidence and Risk Factors of Brief Resolved Unexplained Events in Infants presenting to Pediatrics Department of Bab Elsharya University Hospital". Al-Azhar Journal of Pediatrics, 22, 4, 2019, 629-653. doi: 10.21608/azjp.2019.303590
(2019). 'Incidence and Risk Factors of Brief Resolved Unexplained Events in Infants presenting to Pediatrics Department of Bab Elsharya University Hospital', Al-Azhar Journal of Pediatrics, 22(4), pp. 629-653. doi: 10.21608/azjp.2019.303590
Incidence and Risk Factors of Brief Resolved Unexplained Events in Infants presenting to Pediatrics Department of Bab Elsharya University Hospital. Al-Azhar Journal of Pediatrics, 2019; 22(4): 629-653. doi: 10.21608/azjp.2019.303590

Incidence and Risk Factors of Brief Resolved Unexplained Events in Infants presenting to Pediatrics Department of Bab Elsharya University Hospital

Article 8, Volume 22, Issue 4, October 2019, Page 629-653  XML PDF (1.51 MB)
Document Type: Original Article
DOI: 10.21608/azjp.2019.303590
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Abstract
Background:  Infants who present with a history of an acute event (an unexpected change in an infant's breathing, appearance, or behavior), reported by their parent or caregiver, represent a heterogeneous group of patients of varying ages with diverse pathophysiology. A BRUE is diagnosed only when there is no explanation for the described event after a thorough history and physical examination.
Aim of the study: to detect the incidence of Brief Resolved Unexplained events and differentiate Risk Factors according to initial presentation of cases and follow-up.
Methods: Prospective application of BRUE criteria on infants younger than 12 months old who presented to emergency room of Bab El Shaaria University Hospital from 1 June 2018 to 1 December 2018. BRUE patients were classified into Lower-risk (LR-BRUE) and Higher-risk (HR-BRUE). History was taken from all caregivers and all patients underwent physical examinations and o2 saturation monitoring by pulse oximetry on room air. Studied infants were followed up 3 to 6 months after discharge either by regular visits or by phone.
Results: study included 2462 Infants below 1 years old, the inclusion criteria of BRUE met 39 patients ( 1.58%) 18 of them are males (46 %)  and 21 are females(54%), 23 of BRUE cases classified as low Risk BRUE(59%), and 16 cases as High Risk BRUE(41%) all were admitted for further investigations . prematurity was conducted in 9 cases (23%). The entire BRUE group was monitored by pulse oximetry for 4 hours, O2 saturation was above 90% in 36 cases (93%), while 3 cases (7%) were below 90% and all had been admitted for further assessment and investigations. The incidence of death was in 3 cases (8%) all of them was HR-BRUE. Recurrence occurred in 8 patients (10%) , 2 of them were initially classified as LR-BRUE. The most frequent diagnosis of HR-BRUE was pertusis in 4 cases (25%), GER in 3 cases (19%) and epilepsy in 2 cases (13%).
Conclusion: Diagnosis of BRUE represent 1.58 % of the studied cases, the risk of Recurrence is statistically significant in patient below 2 months old , preterm infants , infants with history of underlying diseases , and those whose O2 saturation above 90%. While the Risk of death was statistically significant in infants with history of underlying diseases, History of NICU admission and those who's presented by high Risk BRUE.
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